Question: What Is The Antidote For Theophylline?

What drugs decrease theophylline levels?

Drug-drug.

Activated charcoal, barbiturates, ketoconazole, phenytoin, rifampin: Decreases theophylline levels.

Monitor patient closely..

What does theophylline interact with?

Other medications can affect the removal of theophylline from your body, which may affect how theophylline works. Examples include cimetidine, disulfiram, fluvoxamine, interferon, mexiletine, propranolol, rifampin, drugs used to treat seizures (such as carbamazepine, phenytoin), St.

Does theophylline increase heart rate?

Heart rate was higher in the theophylline group than in the control group. Both pacemaker therapy and theophylline improved symptom scores after 3 months of treatment; however, a similar improvement was observed in the control group.

What is a normal theophylline level?

Therapeutic serum levels of theophylline are between 10 to 20 mcg/ml. Most adults achieve these concentrations with daily slow-release oral theophylline preparations, 200-400 mg (approximately 10 mg/Kg) twice a day.

When should you take theophylline?

Take theophylline exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Take this medication with a full glass of water on an empty stomach, at least 1 hour before or 2 hours after a meal.

Does coffee interact with theophylline?

theophylline caffeine Avoid drinks or foods that contain caffeine, such as coffee, tea, cola, and chocolate. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs.

Does theophylline cause weight loss?

Common side effects of Theo-24 include mild nausea, loss of appetite, stomach pain, diarrhea, upset stomach, weight loss, restlessness, tremor, sleep problems (insomnia), headache, lightheadedness, dizziness, sweating, restlessness, nervousness, or irritability.

What is the generic name for theophylline?

Theophylline (Elixophyllin, Uniphyl): Side Effects, Dosages, Treatment, Interactions, Warnings.

Is theophylline short or long acting?

Theophylline is available as a pill or as an intravenous (through the vein) drug. It is long-acting and prevents asthma attacks. Theophylline may be used to treat difficult-to-control or severe asthma and must be taken daily.

Why is theophylline not used?

For maintenance therapy of asthma, theophylline may be obsolete because it is merely a relatively weak bronchodilator that adds little but side effects to dose- optimized inhaled ~2-agents … and does not address the underlying inflammation, a fundamental charac- teristic of the disease.

Which antibiotics increase theophylline?

Administration of allopurinol, oral contraceptives, cimetidine, erythromycin, quinolone antibiotics, fluvoxamine, zileuton, and zafirlukast has been shown to increase theophylline levels.

What are the signs and symptoms of theophylline toxicity?

Mechanism of toxicityNervousness.Insomnia.Central respiratory stimulation.Nausea.Vomiting.Tremors.Hyperesthesia.Focal and generalized seizures that progress to status epilepticus in 25%More items…•

What medications can increase the risk of theophylline toxicity?

Causes of chronic theophylline toxicity include the following: Drug interactions (eg, ethanol [ETOH], cimetidine, oral contraceptives, allopurinol, macrolide antibiotics, quinolone antibiotics) Liver disease. Congestive heart failure.

Is there a substitute for theophylline?

Abstract: Doxofylline, which differs from theophylline in containing the dioxalane group at position 7, has comparable efficacy to theophylline in the treatment of respiratory diseases, but with an improved tolerability profile and a favorable risk-to-benefit ratio.

Is theophylline still prescribed?

Theophylline is still one of the most widely prescribed drugs for the treatment of asthma and chronic obstructive pulmonary disease (COPD) worldwide, because it is inexpensive and widely available.

How quickly does theophylline work?

This medication may be used alone or with an inhaled bronchodilator. How fast does this medication work? This medication works within 30 minutes.

How often should theophylline levels be checked?

Question: How often should a theophylline level be taken? Answer: In general, a level should be checked 1-2 times a year after a person is regulated. Of course, a person with variable levels should have his levels checked more often. If trouble breathing increases or side effects appear, then a level should be checked.

Which tea has most theophylline?

black teaTheophylline is found in black tea and to a lesser extent in green coffee, cocoa cotyledon and dried mate. Theophylline is synthesized on an industrial scale and is used principally in pharmaceutical preparations. Per-caput daily intake of theophylline from black tea in the USA has been estimated to be 0.14 mg.

Can you stop theophylline abruptly?

“If you suddenly stop taking theophylline, your asthma symptoms may return, which could lead to a potentially fatal asthma attack.”

Does theophylline cause tachycardia?

What happens to patients with theophylline intoxication? Signs of mild theophylline toxicity are nausea, vomiting, abdominal pain, tachycardia, and muscle tremor and are usually seen with levels around 20 to 25 mg/L.

Is theophylline a stimulant?

Theophylline is a drug derived from methylxanthine (a purine derivative) and has smooth muscle relaxant, bronchial dilation, diuretic, cardiac and central nervous system (CNS) stimulant activities.